Fast dissolving tablet are the novel dosage form which is well accepted now a days by geriatric and pediatric patients as it does not need water to swallow. The aim of the present article is to study the natural polymers and the technology used in fast dissolving tablets. Natural polymers like plantagovata seed mucilage, Mangiferaindicagum, gum karaya, Hibiscus rosasinenses mucilage, dehydrated banana powder, orange peel pectin, Locust bean gum, improve the properties of tablet and used as binder, diluent, superdisintegrant, increase the solubility of poorly water soluble drug, decrease the disintegration time and provide nutritional supplement. Natural polymers are obtained easily from the natural origin and they are cost effective, non-toxic, biodegradable, eco-friendly, devoid of any side effect, renewable and also provide nutritional supplement. It is proved from the studies that natural polymers are more safe and effective than synthetic polymers.
H. S. Sunitha*, S. Parthiban, G. P. Senthil Kumar, T. Tamiz Mani.
Diabetes mellitus is a chronic disease whose global spread has given it the characteristics of a pandemic. The most frequent form is Type 2 diabetes which represents more than 85% of the cases. Other forms are Type 1 (10%), specific diabetes and gestational diabetes (5%). The current work is to evaluate the beneficial effect of dromaius novaehollandiaeon fructose and Alloxan(125mg/kg.Ip./single dose) induced diabetic wistar rats. All the parameters were studied and histopathological studies also performed.
The emerging technology of drug delivery is being applied to phyto‐pharmaceuticals to improve the bioavailability of herbal extracts for medicinal applications. Plant extracts can be standardized accordingly and may be formulated as phytosomes for systematic investigation for any improved potential use. Phytosomal herbal formulations are better absorbed, and as a result produce better bioavailability and actions than the conventional phytomolecules or botanical extracts. The term “Phyto” means plant while “some” means cell-like. It is also often known as herbosomes. Phytosomes are produced by a process whereby the standardized plant extract or its constituents are bound to phospholipids, mainly phosphatidylcholine producing a lipid compatible molecular complex. This phyto-phospholipid complex i.e. phytosome resembles a little cell. Phytosomes exhibit better pharmacokinetic and pharmacodynamic profile than conventional herbal extracts. These drug-phospholipid complexes can be formulated in the form of solution, suspension, emulsion, syrup, lotion, gel, cream, aqueous micro dispersion, pill, capsule, powder, granules and chewable tablet.
V. Ganesan*, Sreekanth. S. Kaithavalappil, M. Kannappan, Deepa. T. Vasudevan.