Among the various causes of death in the world are degenerative diseases such as heart failure, anaemia, Diabetes Mellitus and stroke, which are generally linked to the oxidative stress. The therapeutic benefit of medicinal plants in the treatment of degenerative diseases is attributed to their antioxidant properties. In the present study crude (PH) extract of nine different medicinal plants are used and were evaluated for their quantitative phytochemicals such as flavonoids, phenols, tannins, carbohydrate, alkaloid, saponin, cardiac glycosides and their antioxidant activities using DPPH, reducing  power, hydroxyl radical scavenging, superoxide radical scavenging, Nitric oxide radical scavenging. Total antioxidant activity was done by FTC assay and compared with TBA method. In the present study, results showed that the crude (PH) extract of nine different medicinal plants have found to possess a good antioxidant activity. This activity of PH formulation may be attributed to their free radical scavenging ability. The extent of antioxidant activity of PH was found to be significant. 

Leukemia is an amalgam of cancers and arises due to the malignancy of the any elements of blood and bone marrow. In other terms, they are abnormal white blood cells, which are not fully developed and are called blasts or leukemia cells.  The growth of the Leukemia cells are rapid than Normal cells. As with time, they replace the population of the normal WBCs and RBCs and may spread to the lymph nodes and other organs. As in 2012, 3,52,000 People were affected by Leukemia and 2,65,000 Deaths occurred. It is the most common type of cancer in children and three quarters of Cases being) about 90% of all leukemias are diagnosed in adults, with acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) being most common in adults.

A Simple highly sensitive precise and accurate high performance liquid chromatographic method was developed and validated for the rapid quantification of metaxalone in bulk and its pharmaceutical dosage form. The chromatographic separation was achieved with a reverse phase column C18 (4.6×150mm, 5µm) and the mobile phase consisted of a cetonitrile potassium dihydrogen phosphate buffer methanol in the ratio 40:40:20 v/v, at a flow rate of 1.0ml/min, the injection volume was 10µl with run time of <5min and UV detection was carried out at 279.5nm. The method was validated for specificity, linearity, precision, accuracy, robustness and system suitability. The method was linear in the drug concentration range of 20-100µg/ml the precision (RSD) of six samples was performed for repeatability and the intermediate precision (RSD) among six samples preparation was performed and the mean recovery was 99.7% the proposed method can be used successfully for routine analysis of the drug in bulk and pharmaceutical dosage forms.